Necrotizing Soft-Tissue Infection: Laboratory Risk Indicator for Necrotizing Soft Tissue Infections Score

Necrotizing Soft-Tissue Infections

151 Necrotizing soft-tissue infections have been recognized for centuries. Hippocrates vividly described the disease in the 5th century BC, as follows: ÒThe erysipelas would quickly spread in all directions. Flesh, sinews, and bones fell away in great quantities.Ó Necrotizing soft-tissue infections were subsequently designated as Òstreptococcal gangrene,Ó Òphagedena,Ó and Òphagedena gangrenosum...

Necrotizing Soft Tissue Infections.

The LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score: a tool for distinguishing necrotizing fasciitis from other soft tissue infections.

OBJECTIVE Early operative debridement is a major determinant of outcome in necrotizing fasciitis. However, early recognition is difficult clinically. We aimed to develop a novel diagnostic scoring system for distinguishing necrotizing fasciitis from other soft tissue infections based on laboratory tests routinely performed for the evaluation of severe soft tissue infections: the Laboratory Risk...

Necrotizing Soft Tissue Infections

EVIDENCE DEFINITIONS · Class I: Prospective randomized controlled trial. · Class II: Prospective clinical study or retrospective analysis of reliable data. Includes observational, cohort, prevalence, or case control studies. · Class III: Retrospective study. Includes database or registry reviews, large series of case reports, expert opinion. · Technology assessment: A technology study which doe...

Necrotizing soft-tissue infections.

OBJECTIVE To provide a contemporary review of the diagnosis and management of necrotizing soft-tissue infections. DATA SOURCES Scientific literature and internet sources. STUDY SELECTION Major articles of importance in this area. CONCLUSIONS The mortality for necrotizing soft-tissue infections appears to be decreasing, possibly due to improved recognition and earlier delivery of more effe...